Keratin 5 cre
Web11 jan. 2013 · Keratinocytes were isolated from the tail epidermis of ATG5 f/f and ATG5 f/f K5-Cre mice. RT-PCR analysis was performed with primers specific for keratin K5, Cre recombinase and ATG5. Protein lysates were electrophoresed through polyacrylamide gels and subjected to Western blot analysis using first step antibodies against LC3 and p62. Web10 jan. 2024 · Unlike its family member p53, TP63 is rarely mutated in human cancer. However, Delta Np63 alpha protein levels are often elevated in tumors of epithelial origin, …
Keratin 5 cre
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Web1 jan. 2007 · The keratin 5‐Cre recombinase (K5Cre) transgenic mouse line has been used to generate skin specific gene deletions. We found that the K5Cre mice display a unique … Web6 sep. 2024 · Bevriezing met vloeibare stikstof (cryotherapie) is een veel toegepaste behandelmethode van actinische keratose (arbitrair ≤ 5 laesies). 2 Er worden hiermee …
WebSTOCK Tg(KRT14-cre)1Amc/J. KRT14, keratin 14 (human) Cre recombinase activity is reported in skin, the oral ectoderm including the dental lamina at 11.75 d.p.c., and the … Web28 jan. 2024 · Subsequent studies using conditional Piga inactivation with keratin 5-Cre (K5Cre), expressed in basal cells of the skin, revealed lethality within a few days of birth due to abnormal skin development , reinforcing the importance of …
WebGeneRIFs: Gene References Into Functions. NMHC IIA may play critical roles in the early trophoblast-derived ectoplacental cone and extraembryonic ectoderm in Keratin 5-Cre transgenic mice. G to A substitution in all affected animals. This mutation leads to an amino acid change of glutamic acid to lysine in the final E (478) of the KLLEGE motif ... Web1 jun. 2003 · Keratin K5 is expressed in the basal layer of stratified epithelia in mammals and its synthesis is regulated by hormones and vitamins such as retinoic acid.
WebFor example, tamoxifen-induced deletion of the gene encoding Stat-3 specifically in keratinocytes (under the control of the keratin 5 promoter) resulted in reduced inflammation compared to wild-type animals upon their treatment with imiquimod. 3 In contrast, transgenic mouse models in which Stat-3 was knocked out in T cells by Cre recombinase under the …
Web1 mei 2004 · To investigate the effect of skin specific ectopic IL-17A overexpression, the IL-17A ind mouse was crossed to keratin 14-Cre mice (K14 Cre ) [99] yielding K14-IL-17A … expanded liability definitionWebTissue proteome. GENERAL INFORMATIONi. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions … bts headphones amazonWebWe previously demonstrated that LY6D + luminal prostate progenitor cells are intrinsically resistant to androgen deprivation in non-tumor-prone mice. 6 To investigate whether LY6D + luminal cells also play a significant role for CR PCa, we employed a conditional mouse model, allowing for tumor initiation at any given time by systemic administration of … bts healing songsWebA keratinocyte-specific Cre transgenic construct (pK5-Cre) containing the keratin 5 promoter, Cre recombinase gene and polyA of human growth hormone gene was … bts headphones not renewingWebAbstract. Three mouse lines expressing Cre recombinase under the control of the human K14 promoter induced specific deletion of loxP flanked target sequences in the … bts healing therapyWebDownload (PPT) Figure 5 No difference in DMBA-induced keratinocyte apoptosis in K5-ΔNp63αtg/tg compared with wild-type mice. (a) IHC analysis using an α-active caspase-3 … bts headingexpanded library outward