2024 Purple hand syndrome phenytoin

Purple hand syndrome phenytoin

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WebNov 23, 2024 · Raynaud's (ray-NOSE) disease causes some areas of the body — such as fingers and toes — to feel numb and cold in response to cold temperatures or stress. In Raynaud's disease, smaller arteries that supply blood to the skin narrow. This limits blood flow to affected areas, which is called vasospasm. Raynaud's phenomenon. Raynaud … WebKeywords: Amputation, general anaesthesia, phenytoin, purple glove syndrome. INTRODUCTION. Intravenous (IV) administration of phenytoin can result in soft tissue injury at the site of injection leading to oedema and purplish-black discolouration of the hand. This is known as the purple glove syndrome (PGS).

[Purple hand syndrome and intravenous phenytoine] - PubMed

WebSep 16, 2015 · The authors point out that purple glove syndrome is a rare condition that almost always occurs after intravenous administration of phenytoin. The purple discoloration typically occurs distal to the site of intravenous phenytoin administration. What makes this case unique is that it occurred after 20 days of oral therapy in a patient … WebRarer cutaneous side effects include drug-induced lupus, purple hand syndrome, pigmentary alterations and IgA bullous dermatosis. Phenytoin can effect clotting function and alter … darlington raceway winner today

A Rare Complication of Phenytoin Infusion in Newborn: Purple …

WebSep 15, 2024 · Intravenous phenytoin administration may rarely be complicated by the Purple Glove Syndrome. The basic pharmacology, presentation, and management of … WebDec 1, 1992 · Medicine. Journal of Neuroscience Nursing. &NA; Intravenous phenytoin, available for use since 1956, has several well known adverse effects, such as … WebSep 1, 2024 · Purple glove syndrome (PGS) is an atypical adverse drug reaction that can occur after the administration of intravenous phenytoin. Although definitions of PGS vary, it has been loosely defined as signs and symptoms of progressive edema, discoloration, and pain that occurs following administration of intravenous phenytoin [1] . darlington raceway winners list

(PDF) Purple glove syndrome following intravenous …

Warfarin and phenytoin drug interaction with possible purple glove syndrome

WebPurple glove syndrome (PGS) is a rare complication of intravenous phenytoin use that typically presents with pain, edema, and discoloration at the injection site that spreads to … WebThe purple-blue discoloration and edema of the right hand and arm. Purple Glove syndrome is a rare complication of intravenous phenytoin infusion. The incidence ranges from 1.7% to 5.9% Purple Glove syndrome can occur with or without clinically apparent extravasation. Highly alkaline phenytoin solution may induce vasoconstriction, which results ... bismuth allotropyWebJun 28, 2024 · PGS is a rare serious adverse reaction to intravenous phenytoin. Its incidence ranges from 1.5 to 5.9% [ 1 ]. Its manifestation includes pain, skin discolouration, blister formation, sloughing, ulceration, and necrosis. Usually clinical manifestations are limited to the superior limbs but there are descriptions of cases with involvement of ... bismuth alchemy

"WebSep 1, 2024 · Purple glove syndrome (PGS) is an atypical adverse drug reaction that can occur after the administration of intravenous phenytoin. Although definitions of PGS vary, … " - Purple hand syndrome phenytoin

Purple hand syndrome phenytoin

Purple glove syndrome: A looming threat. - Abstract - Europe PMC

WebIntravenous phenytoin, available for use since 1956, has several well known adverse effects, such as hypotension, arrhythmias and toxicity. Purple glove syndrome is a less common … WebJan 1, 2016 · An uncommon but serious adverse drug reaction after phenytoin administration is known as purple glove syndrome (PGS). Initial presentation is characterized by pain, skin discoloration, and edema ...

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WebNational Center for Biotechnology Information WebKeywords: Amputation, general anaesthesia, phenytoin, purple glove syndrome. INTRODUCTION. Intravenous (IV) administration of phenytoin can result in soft tissue …

WebThe patient’s right hand was cool with a purple mottling spreading from the IV site. Her attending physician was notified, and warm compresses with elevation were applied to … WebThe side effects of phenytoin continue to create significant morbidity. Common side effects include gingival hyperplasia, coarsening of the facies, and hirsutism. Rarer cutaneous side …

WebJul 2, 2015 · In her 1992 publication, Hanna named a delayed, soft tissue injury of the hand and forearm following IV administration of phenytoin “purple glove syndrome” (PGS) [4, 5]. Increasing reports of this condition have recently emerged, some involving permanent tissue damage or loss, leading to questions regarding the safety and risk-benefit profile of IV … WebVascular Medicine 2007; 12: 29–31 Purple glove syndrome following intravenous phenytoin administration Reena Chokshi, John Openshaw, Nehal N Mehta and Emile Mohler III Abstract: Purple glove syndrome …

WebOct 1, 1998 · Objective: To determine the incidence, risk factors, and long-term sequelae of the purple glove syndrome (PGS) in hospital patients receiving IV phenytoin. Background: PGS is a poorly understood, potentially serious local complication of IV phenytoin administration characterized by progressive distal limb edema, discoloration, and pain. …

WebJan 1, 2024 · Purple Glove Syndrome (PGS) is a rare complication of intravenous phenytoin administration which is illustrated by delayed soft tissue injury of the skin conterminous … bismuth allergyWebOct 1, 1998 · Objective: To determine the incidence, risk factors, and long-term sequelae of the purple glove syndrome (PGS) in hospital patients receiving IV phenytoin. Background: … bismuthaltige quadrupeltherapieWebJan 1, 2024 · Acral manifestations of systemic diseases: drug induced Purple glove syndrome. Phenytoin has been used for the treatment of seizures since 1956. It is administered intravenously in emergency departments and hospitals to patients with isolated seizures or undergoing neurosurgical procedures, who are unable to receive oral … darlington raceway weekend schedulehttp://patientsafety.pa.gov/ADVISORIES/Pages/200612_12.aspx bismuth affaireWebJul 1, 2010 · A 60-year-old woman was admitted in a peripheral hospital for frontal bone fracture following road traffic accident (RTA) with normal brain parenchyma and generalized tonic-clonic seizure, for which she received 900 mg of loading dose of phenytoin dissolved in 100 ml of normal saline through a 22-gauge peripheral intravenous catheter kept in her … bismuth alloy melting pointWebSep 1, 2003 · Sixty-one doses of phenytoin were administered in the PICU, 38 in the four medical and one surgical wards, and one in the A & E department. In 88 exposures, the i.v. cannula was placed in the upper limb (antecubital fossa or dorsum of the hand); in 12 the cannula was inserted in the lower limb (dorsum of foot or femoral vein within the groin). darlington racingWebFeb 9, 2024 · pinpoint red spots on the skin. red skin lesions, often with a purple center. red, irritated eyes. redness and swelling of the gums. slow or irregular heartbeat. sore throat. sores, ulcers, or white spots on the lips or in the mouth. stomach pain. swollen, painful, or tender lymph glands in the neck, armpit, or groin. bismuth alloy vs lead