WebFeb 8, 2024 · Examples of classes of medications with anticholinergic properties include antihistamines (eg, diphenhydramine), tricyclic antidepressants (TCAs; eg, amitriptyline), sleep aids (eg, doxylamine), cold preparations, scopolamine (hyoscine), and tainted illicit street drugs (eg, heroin "cut" with scopolamine). WebJul 22, 2024 · QT (QTc) Prolongation is associated with many psychotropic medications (especially antipsychotics) and some are linked to serious ventricular arrhythmias (e.g. - …
Antihistamine activity, central nervous system and ... - PubMed
WebFeb 15, 2005 · Diphenhydramine overdose in one of the frequent reported causes of acute poisoning. Patients with diphenhydramine overdose can present with central nervous system manifestations, anticholinergic manifestations and cardiovascular symptoms. WebDiphenhydramine toxicity; anticholinergic toxidrome; rhabdomyolysis; QTC prolongation 1. Introduction Diphenhydramine is a commonly used and widely available over the counter antihistaminic drug, used for allergic reactions as a compound in cold medicines, and as a sleeping aid [1,2]. Pharmacologically, this is denada rroji
Diphenhydramine Toxicity - StatPearls - NCBI Bookshelf
WebMar 1, 2015 · Transdermal scopolamine (Transderm Scop) is preferred over antihistamines for prevention of motion sickness in persons desiring wakefulness during travel. 15 It can be used for up to 72 hours per... WebIntroduction. A number of psychotropic drugs, including antipsychotics and antidepressants, are shown to prolong the QT interval (QTc) (i.e., the interval reflecting electrical depolarization and repolarization of the ventricles).1 Different formulas (Bazett’s, Framingham, Hudges, etc.), each with its own set of limitations, are used to correct the QT … WebOct 1, 2015 · The duration of QTc interval is the major determinant of the risk of drug-induced TdP. Congenital long QT syndrome (LQTS), female gender, hypokalemia, and use … denacifikacija sta znaci