WebA thiazide is any of a group of diuretics that act by inhibiting the reabsorption of sodium and chloride in the in the distal renal tubule. This action results in increased sodium and free … WebA thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812) Type ... Mechanism of action. As a diuretic, chlorothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium ...
DRUG CLASSES THIAZIDE AND THIAZIDE-LIKE DIURETICS
WebHydrochlorothiazide is a thiazide diuretic. Thiazides affect the renal tubular mechanisms of electrolyte reabsorption, directly increasing the excretion of Sodium and Chloride in approximately equivalent amounts. ... Indirectly, the diuretic action of Hydrochlorothiazide reduces plasma volume with consequent increases in plasma renin activity ... WebOverview. Thiazides are used to relieve oedema due to chronic heart failure and, in lower doses, to reduce blood pressure. Loop diuretics are used in pulmonary oedema due to left ventricular failure and in patients with chronic heart failure. Combination diuretic therapy … avalon fm30
Thiazide Diuretics Concise Medical Knowledge - Lecturio
WebThiazide diuretics, which are the most prescribed diuretic, inhibit the sodium-chloride transporter in the distal tubule. Because this transporter normally only reabsorbs about … WebThe mechanism of action for thiazide diuretics is inhibiting the apical sodium/chloride transporter in epithelial cells of the distal convoluted tubules to reduce ECF and cardiac output. Thiazide diuretics such as hydrochlorothiazide and indapamide are ideal first-line antihypertensive agent as proven through multiple clinical trials. In ... Web11 Apr 2024 · Abstract. The term thiazide is universally understood to refer to diuretics that exert their principal action in the distal tubule. The thiazide class is heterogenous and can be further subdivided into compounds containing the benzothiadiazine ring structure—the thiazide-type (e.g., hydrochlorothiazide)—and those lacking the benzothiadiazine ring—the … avalon fm20